Characteristic | Monotherapy n = 84 | Combination therapy n = 205 | P value |
---|---|---|---|
Mean (SD) age, years | 72.6 (10.3) | 71.7 (11.2) | 0.515 |
Range | 39–91 | 39–94 | |
Sex, n (%) | 0.266 | ||
Female | 44 (52.4) | 122 (59.5) | |
Male | 40 (47.6) | 83 (40.5) | |
Race/Ethnicity, n (%) | 0.007 | ||
White | 34 (40.5) | 108 (52.7) | |
Black | 2 (2.4) | 7 (3.4) | |
Asian | 6 (7.1) | 1 (0.5) | |
Other | 0 (0.0) | 1 (0.5) | |
Not recorded in chart | 42 (50.0) | 88 (42.9) | |
Diagnosis, n (%) | 0.671 | ||
BRVO | 44 (52.4) | 113 (55.1) | |
CRVO | 40 (47.6) | 92 (44.9) | |
Mean (SD) duration of ME, months | 25.6 (26.4) | 15.5 (21.4) | <0.001 |
Range | 0–100 | 0–150 | |
Previous treatment for RVO, n (%) | 70 (83.3) | 178 (86.8) | 0.439 |
Intravitreal anti-VEGF, n (%) | 51 (60.7) | 154 (75.1) | 0.014 |
Bevacizumab | 44 (52.4) | 137 (66.8) | |
Ranibizumab | 11 (13.1) | 29 (14.1) | |
Pegaptanib | 0 (.0) | 3 (1.5) | |
Ranibizumab and/or bevacizumab | 51 (60.7) | 152 (74.1) | |
Mean (SD) number of ranibizumab and/or bevacizumab injections in these patients | 5.2 (4.6) | 4.5 (5.1) | 0.383 |
Intravitreal triamcinolone, n (%) | 44 (52.4) | 71 (34.6) | 0.005 |
Laser photocoagulation, n (%) | 43 (51.2) | 69 (33.7) | 0.005 |
Focal | 33 (39.3) | 52 (25.4) | 0.018 |
Panretinal | 15 (17.9) | 30 (14.6) | 0.493 |
Pars plana vitrectomy, n (%) | 12 (14.3) | 25 (12.2) | 0.629 |
Glaucoma or OHT at baseline, n (%) | 0.438 | ||
Yes | 27 (32.1) | 64 (31.2) | |
No | 40 (47.6) | 111 (54.1) | |
Not recorded in chart | 17 (20.2) | 30 (14.6) | |
Using IOP-lowering medication at baseline, n (%) | 20 (23.8) | 54 (26.3) | 0.505 |
History of IOP response to steroid, n (%) | 0.065 | ||
Yes | 12 (14.3) | 33 (16.1) | |
No | 42 (50.0) | 126 (61.5) | |
Not recorded in chart | 30 (35.7) | 46 (22.4) | |
Lens status, n (%) | 0.069 | ||
Phakic | 29 (34.5) | 99 (48.3) | |
Pseudophakic | 54 (64.3) | 104 (50.7) | |
Not recorded in chart | 1 (1.2) | 2 (1.0) | |
Mean (SD) BCVA, lines | 9.1 (4.7) | 10.1 (4.6) | 0.095 |
Snellen | 20/125 | 20/100 | |
Mean (SD) CRT, μm | 465 (177) | 427 (183) | 0.136 |