Parameter, n (%) | Monotherapy n = 84 | Combination therapy n = 205 | P Value |
---|---|---|---|
At any time during study | |||
Increase from baseline ≥10 mm Hg | 20 (23.8) | 71 (34.6) | 0.072 |
Post-baseline IOP ≥25 mm Hg | 21 (25.0) | 76 (37.1) | 0.048 |
Post-baseline IOP ≥35 mm Hg | 5 (6.0) | 22 (10.7) | 0.205 |
At final visit | |||
Increase from baseline ≥10 mm Hg | 3 (3.6) | 9 (4.4) | >0.999 |
IOP ≥25 mm Hg | 3 (3.6) | 11 (5.4) | 0.764 |
IOP ≥35 mm Hg | 1 (1.2) | 4 (2.0) | >0.999 |
Glaucoma surgery (laser/incisional) | 1 (1.2) | 8 (3.9) | 0.455 |
Laser | 1 (1.2) | 3 (1.5) | >0.999 |
Incisional | 0 (0.0) | 5 (2.4) | 0.326 |
IOP-lowering medication used secondary to retina treatment | 20 (23.8) | 64 (31.2) | 0.208 |