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Table 1 Pupil response metrics in four study populations using the Portable Field Dark Adaptometer (2010–2013)

From: A novel device for assessing dark adaptation in field settings

Country, Assessment Year

Bangladesh, 2010

Kenya, 2010

Zambia, 2012

Peru, 2013

Study Population

Pregnant women

School-aged children

Preschool-aged children

Adults

 n

242

184

305

91

 Male, n (%)

0 (100.0)

79 (43.0)

148 (48.5)

44 (48.4)

 Mean age ± SD

23.4 ± 6.1

9.2 ± 1.9

5.7 ± 1.3

55.1 ± 10.9

Mean relative change ± SD in pupil diameter (%)1

   

 All stimuli: -2.9 to 0.1 log cd/m2

−19.8 ± 5.0

−15.5 ± 5.8

−17.0 ± 6.8

−22.7 ± 8.0

 Low intensity: −2.9 to −1.3 log cd/m2

−14.5 ± 5.3

−9.4 ± 5.1

−9.2 ± 5.9

−16.3 ± 7.6

 High intensity: −0.9 to 0.1 log cd/m2

−26.2 ± 5.4

−23.1 ± 7.5

−26.7 ± 8.3

−30.5 ± 8.8

Mean response time (s) 2

    

 All stimuli: −2.9 to 0.1 log cd/m2

1.27 ± 0.31

1.02 ± 0.16

1.11 ± 0.21

1.13 ± 0.18

 Low intensity: −2.9 to −1.3 log cd/m2

1.21 ± 0.29

0.90 ± 0.19

1.00 ± 0.21

1.07 ± 0.22

 High intensity: −0.9 to 0.1 log cd/m2

1.35 ± 0.44

1.17 ± 0.17

1.24 ± 0.25

1.20 ± 0.22

Mean +/- SD pupillary threshold (log cd/m2)

−1.87 ± 0.75

−1.20 ± 0.83

−1.34 ± 0.70

−1.91 ± 0.81

Distribution of pupillary thresholds (%)3

    

 Good: −2.9 to −2.1 cd/m2

49.2

23.4

20.7

59.3

 Adequate: −1.7 to −0.9 cd/m2

42.1

42.9

55.3

29.7

 Impaired: −0.5 to 0.1 cd/m2

8.7

33.7

24.0

11.0

  1. 1Pre- to post-stimulus change pupil diameter (in pixels), expressed as proportion of pre-stimulus diameter; figures are mean +/- SD; lower values reflect a greater response/better dark adaptation
  2. 2Absolute value of the difference in video frame number from pre- to post-stimulus, divided by 30 frames/s; higher values reflect a faster response/better dark adaptation
  3. 3Pupillary threshold defined as first stimulus at which pupil diameter decreased by 20 % or more; abnormal as defined by Congdon et al. [8], i.e., pupillary threshold > = −0.5 log cd/m2