Fig. 2

Results of hematoxylin & eosin (HE) and immunohistochemical staining of the neoplasm in the right cornea. a Regularly arranged multilayer squamous epithelial cells are seen on the surface of the neoplasm; no keratinization or atypia is observed. Numerous fibroblast-like cells are seen proliferated subepithelially, with a small amount of well-differentiated mature collagen fibers among them (HE × 100). b Microscopic examination under high magnification shows long, spindle- or bean-shaped cells, with abundant cytoplasm, arranged in bundles (HE × 400). c Brown pigment particles are seen among the tumor cells (HE × 400). d Tumor cells showing a high expression of vimentin (EnVision × 200). e Tumor cells showing SMA expression (EnVision × 200). f A proportion of the tumor cells expressing desmin (EnVision × 200). g The vascular endothelial cells among the tumor cells show CD34 expression (EnVision × 200). h No S100p expression is seen in the tumor cells (EnVision × 200)