Fig. 2
From: Ocular transient receptor potential channel function in health and disease
TRP channels and CB1 in the posterior section of the eye: Retina: TRPV1 [57], CB1 [57], TRPM7 [139], TRPM8 [57], TRPA1 [57], TRPM1 [51]. TRPs marked with an asterisk were detected in retinoblastoma cells. Interestingly, TRPA1 could not be detected in etoposide-resistant retinoblastoma cells [57]; retinal pigment epithelium: TRPV1 [58, 59], TRPV2-4 [58], TRPM8 [58], TRPMA1 [58]; choroid: TRPV1 and CB1 [58], TRPM8 and TRPA1 [58], TRPs marked with an asterisk were also detected in uveal melanoma cells. Notably, the gene expression of TRPM8 is at lower levels in uveal melanoma cells whereas the TRPA1 expression is at higher levels in healthy uvea [58]