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Table 2 Summary of the studies on MSC in treating corneal diseases

From: Mesenchymal stem cells for treating ocular surface diseases

Cornea anomalies

 

Species

Application

Reference

Inherited cornea anomalies

Lumican null

Mouse

Intrastromal injection

[44]

 

MPS IIV

Mouse

Intrastromal injection

[57]

Cornea Chemical burn

 

Mouse

Intrastromal injection

[58]

  

Rat

Cornea surface transplantation

[37]

  

Rat

Topical application

[59]

  

Rat

Subconjunctival injection

[60]

  

Rabbit, rat, mouse

Systematically application

[63–65]

Persistent cornea epithelium defect

 

Human

Cornea leision injection

[66]

GVH dry eye

 

Human

Blood infusion

[67]

  1. This table summarizes the current research on MSC treating corneal diseases both in animal and human. The MSC application methods are specified
  2. PMS IIV Mucopolysaccharidosis type VII