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Fig 3 | BMC Ophthalmology

Fig 3

From: Diabetic levels of glucose increase cellular reducing equivalents but reduce survival in three models of 661W photoreceptor-like cell injury

Fig 3

a Total intracellular NADPH levels in unstressed 661W photoreceptor-like cells were not significantly altered by exposure to 25mM glucose. Phototoxic stimuli and oxidative stress induced by H2O2 but not exposure to the apoptosis inducing agent reduced total intracellular NADPH levels significantly, however exposure to excess glucose significantly increased total NADPH levels in all injury models relative to similarly treated photoreceptor-like cells exposed to 5mM glucose. b Total intracellular NADH levels were not significantly altered by excess glucose in either untreated or injured 661W cells. * indicate P < 0.05 between cells treated in the presence of 5mM and 25mM glucose

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BMC Ophthalmology

ISSN: 1471-2415

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