Multiplex cytokine levels of aqueous humor in acute primary angle-closure patients: fellow eye comparison

BMC Ophthalmology

Table 5 Correlations between Cytokines and relevant factors in APAC patients

	Age		IOP		Number of Glaucoma Medications		AL		ACD		LT		VCD
	ρ	P value	ρ	P value	ρ	P value	ρ	P value	ρ	P value	ρ	P value	ρ	P value
G-CSF	−0.232	0.173	0.506	0.002*	0.464	0.004*	−0.060	0.729	−0.074	0.670	0.121	0.482	−0.097	0.572
IL-6	−0.115	0.503	0.424	0.010	0.443	0.007*	−0.089	0.605	0.031	0.860	0.040	0.815	−0.132	0.444
IL-8	−0.143	0.406	0.375	0.024	0.439	0.007*	−0.198	0.246	0.056	0.743	0.004	0.980	−0.201	0.239
MCP-1	−0.097	0.573	0.291	0.085	0.285	0.092	−0.110	0.523	0.040	0.817	−0.002	0.989	−0.140	0.414
MCP-3	−0.127	0.460	0.420	0.011	0.347	0.038	−0.040	0.816	0.005	0.977	0.177	0.300	−0.108	0.531
MDC	−0.261	0.125	0.201	0.240	0.131	0.445	−0.411	0.013	0.193	0.259	−0.182	0.288	−0.364	0.029
MIP-1β	−0.166	0.335	0.387	0.020	0.395	0.017	−0.130	0.450	0.003	0.985	0.029	0.865	−0.126	0.463
VEGF	0.013	0.941	0.318	0.058	0.198	0.247	−0.051	0.769	−0.091	0.597	0.300	0.075	−0.185	0.280

Relevant factors: Age, intraocular pressure (IOP), Number of Glaucoma Medications, Axial Length (AL), Anterior Chamber Depth (ACD), Lens Thickness (LT), Vitreous Chamber Depth (VCD) and Choroidal Thickness in the Macular Region (CT)
Granulocyte colony-stimulating factor (G-CSF), interleukin (IL)-6, IL-8, monocyte chemotactic protein (MCP)-1, MCP-3, macrophage-derived chemokine (MDC), macrophage inflammatory protein (MIP)-1β, and vascular endothelial growth factor (VEGF)
Correlation coefficient (ρ) and P values are calculated by Spearman’s correlation
*Significance level at 5 % (P < 0.0071) by Bonferroni correction for multiple comparisons

ISSN: 1471-2415