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Fig. 4 | BMC Ophthalmology

Fig. 4

From: Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model

Fig. 4

ROS accumulation and activation of ASK1/p38 signal pathway in Mice Corneal Endothelium of Dysfunctional Allografts a Representative results of ROS staining on corneal endothelium in syngenic group and allogenic group; b Up-regulation of phospho-ASK1 on corneal endothelium in syngenic group and allogenic group by immunofluorescence detection; c Up-regulation of phospho-p38 on corneal endothelium in syngenic group and allogenic group by immunofluorescence detection. Samples of corneal endothelium in syngenic group were used as the control group. 2 corneal grafts from each of the two groups were used for the detection of staining. That is, one corneal graft was separated into two pieces, and one piece was used for the staining of phospho-ASK1. The other was used for staining of phospho-p38

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