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Table 3 Changes in choroidal thickness, retinal thickness and retinal nerve fiber layer thickness during ranibizumab treatment

From: Peripapillary choroidal thickness after intravitreal ranibizumab injections in eyes with neovascular age-related macular degeneration

  Baseline 3 months P value* 6 months P value*
Subfoveal CT (μm) 228.6 ± 78.6 213.8 ± 75.5 <0.001 214.1 ± 72.8 <0.001
Peripapillary CT (μm)
 Mean 153.2 ± 45.3 149.6 ± 43.8 0.156 150.0 ± 43.4 0.187
 Superior 165.2 ± 49.5 162.2 ± 48.7 0.252 162.6 ± 47.8 0.330
 Nasal 153.2 ± 43.0 151.6 ± 43.3 0.532 150.8 ± 42.7 0.378
 Inferior 127.3 ± 40.0 125.1 ± 38.3 0.321 125.9 ± 37.5 0.555
 Temporal 167.1 ± 54.5 159.4 ± 50.8 0.010 160.6 ± 49.6 0.011
Central RT (μm) 300.4 ± 93.0 233.6 ± 62.0 0.001 232.9 ± 61.9 0.001
Peripapillary RT (μm)
 Mean 282.8 ± 19.7 279.9 ± 22.1 0.009 279.8 ± 20.2 0.033
 Superior 303.0 ± 28.3 301.6 ± 30.1 0.169 300.7 ± 26.9 0.171
 Nasal 250.4 ± 22.1 251.0 ± 26.7 0.732 251.0 ± 22.9 0.812
 Inferior 300.4 ± 22.0 300.2 ± 24.8 0.829 298.2 ± 22.7 0.246
 Temporal 276.8 ± 21.2 267.0 ± 20.1 <0.001 269.3 ± 21.9 0.015
RNFL thickness (μm)
 Mean 111.7 ± 11.4 112.9 ± 10.6 0.666 113.1 ± 11.9 0.611
 Superior 130.4 ± 17.5 131.8 ± 16.3 0.736 134.0 ± 16.4 0.373
 Nasal 89.3 ± 15.8 92.2 ± 18.9 0.478 90.4 ± 19.3 0.790
 Inferior 135.1 ± 16.9 137.9 ± 17.0 0.439 138.6 ± 18.9 0.350
 Temporal 92.1 ± 16.2 89.4 ± 13.4 0.379 89.4 ± 16.0 0.385
  1. Continuous variables are expressed as mean ± standard deviation
  2. *Comparison of the parameters in each AMD group visit; P value was based on the paired t-test
  3. CT choroidal thickness, RT retinal thickness, RNFL retinal nerve fiber layer