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Fig. 6 | BMC Ophthalmology

Fig. 6

From: Correlation between optic nerve head circulation and visual function before and after anti-VEGF therapy for central retinal vein occlusion: prospective, interventional case series

Fig. 6

Correlation between optic nerve head (ONH) circulation and arteriovenous passage time or visual function. Correlation between the baseline mean blur rate (MBR) at the ONH and the baseline arteriovenous passage time, the best-corrected visual acuity (BCVA) at 6 months, or mean retinal sensitivity at 6 months is presented. To exclude the influence of systemic circulation and blood flow of ONH tissue, the corrected MBR was calculated as; (MBR of ONH vessel area – MBR of ONH tissue area) in the affected eye ÷ (vascular MBR – tissue MBR) in the healthy fellow eye [11]. a: Correlation between the baseline corrected MBR at the ONH and the arteriovenous passage time at the baseline. The corrected MBR is significantly correlated with the arteriovenous passage time on fluorescein angiography (r = -0.807, P <0.001). The solid line represents the linear regression line (y = -16.102x + 24.200). b: Correlation between the baseline corrected MBR at the ONH and BCVA in logMAR units at 6 months after the initial treatment. The corrected MBR is significantly correlated with the BCVA at 6 months (r = -0.651, P <0.001). The solid line represents the linear regression line (y = -1.036x + 0.983). c: Correlation between the baseline corrected MBR at the ONH and mean retinal sensitivity at 6 months. The corrected MBR is significantly correlated with the retinal sensitivity at 6 months (r = 0.485, P = 0.005). The solid line represents the linear regression line (y = 11.059x + 13.378)

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