Table 1 Clinical data of the patients and histological characteristics of the uveal melanomas

Number of patients

49

28

21

Sex

 Female

21 (42.9 %)

13 (26.5 %)

8 (16.3 %)

0.894

−0.019

 Male

28 (57.1 %)

15 (30.6 %)

13 (26.5 %)

LTD (mm)

 Median

15^a

15.5^b

15^b

0.164

0.208

 Range

5–30

10–30

5–28

Height (mm)

 Median

7^c

7.5^a

6^b

0.263

0.175

 Range

2–22

2-

2–12

Ciliary body invasion

22^d (44.9 %)

16 (57.1 %)

6^d (28.6 %)

0.108

0.230

Scleral invasion

46^d (93.9 %)

26 (92.9 %)

20^d (95.2 %)

0.247

−0.149

Extrascleral extension

7^e (14.3 %)

5^d (17.9 %)

2^d (9.5 %)

0.058

−0.282

Invasion

 of Bruch’s membrane

27^d (55.1 %)

16 (57.1 %)

11^d (52.4 %)

0.732

0.050

 of the optic nerve head

2^d (4.1 %)

1 (3.6 %)

1^d (4.7 %)

0.560

−0.088

Histological subtype

 Epithelioid

9 (18.4 %)

8 (28.6 %)

0 (0 %)

0.005

0.387

 Mixed

22 (44.9 %)

12 (42.9 %)

11 (52.4 %)

 Spindle cell

18 (36.7 %)

8 (28.6 %)

10 (47.6 %)

TNM

 Stage I

5^f (10.9 %)

0^d (0.0 %)

5^c (26.3 %)

0.073

0.264

 Stage II

10 (21.7 %)

6 (22.2 %)

4 (21.1 %)

 Stage III

16 (34.8 %)

11 (40.7 %)

5 (26.3 %)

 Stage IV

15 (32.6 %)

10 (37.0 %)

5 (26.3 %)

High CD105 expression

26^d (54.2 %)

18^d (66.7 %)

8 (38.1 %)

0.098

0.237

High vWF expression

26 (53.1 %)

18 (64.3 %)

8 (21.1 %)

0.129

0.216

VM

25 (51.0 %)

19 (67. %)

6 (28.6 %)

0.016

0.342