Fig. 4From: New histopathologic and ultrastructural findings in Reis-Bücklers corneal dystrophy caused by the Arg124Leu mutation of TGFBI geneDirect sequencing of exon 4 of the TGFBI gene isolated from normal control and III:10. The sequence of a normal control (left) displayed CGC nucleotides in codon 124. The sequence of III:10 (right) showed a G to T transition at the second nucleotide position in the same codon (arrow), which results in an Arg124Leu substitutionBack to article page