Aqueous humor polymerase chain reaction in uveitis – utility and safety

Chronopoulos, Argyrios; Roquelaure, Daniel; Souteyrand, Georges; Seebach, Jörg Dieter; Schutz, James Scott; Thumann, Gabriele

doi:10.1186/s12886-016-0369-z

BMC Ophthalmology

Table 2 Patient demographics

From: Aqueous humor polymerase chain reaction in uveitis – utility and safety

	Age	Working Diagnosis	PCR	CMV	HSV	VZV	EBV	Toxoplasma	Treatment altered
1	22	Uveitis posterior, Adamantiadis-Behçet	neg
2	47	Toxoplasma retinitis	pos*					+	yes
3	28	Uveitis anterior, Posner Schlossman	pos^,*			+	(+)
4	30	Uveitis posterior, ARN	pos			+			yes
5	54	Recurrent granulomatous anterior uveitis	neg						yes
6	32	Recurrent nongranulomatous anterior uveitis	neg
7	78	Recurrent granulomatous anterior uveitis with iris atrophy	pos			+			yes
8	14	Toxoplasma retinitis	pos					+	yes
9	31	Toxoplasma retinitis	pos					+	yes
10	52	Posterior uveitis, Birdshot	neg
11	23	Uveitis posterior, Adamantiadis-Behçet	neg
12	47	Anterior uveitis, suspicion on FUS	pos		+
13	61	Posterior uveitis, ARN	pos*			+
14	26	Posterior uveitis, Adamantiadis-Behçet	neg
15	30	Posterior uveitis, Adamantiadis-Behçet	neg
16	22	Acute anterior uveitis	neg
17	47	Acute anterior uveitis	neg
18	78	Intermediate uveitis	neg
19	41	Anterior uveitis	neg
20	43	Panuveitis granulomatous	pos					+	yes
21	20	Panuveitis	neg
22	58	Panuveitis, Adamantiadis-Behçet	pos					+	yes
23	29	Anterior uveitis, nongranulomatous, hypertensive	neg						yes
24	73	Posterior uveitis, ARN	pos*				+		yes
25	27	Posterior uveitis	pos**		(+)			+
26	19	Panuveitis	pos					+	yes
27	23	Panuveitis	pos**				(+)	+	yes
28	54	Anterior uveitis, Posner Schlossman	pos	+					yes
29	36	Anterior uveitis, Posner Schlossman	neg*						yes
30	45	Anterior uveitis, Posner Schlossman	pos	+					yes
31	65	Anterior uveitis, suspicion FUS	pos		+				yes
32	28	Posterior uveitis, vasculitis	neg
33	39	Posterior uveitis, VKH	neg
34	26	Posterior uveitis	neg
35	68	Posterior uveitis	neg
36	68	Posterior uveitis, Toxoplasma retinitis	pos					+
37	58	Panuveitis, occlusive vasculitis	neg
38	22	Posterior uveitis, vasculitis	neg
39	39	Panuveitis	neg
40	81	Anterior uveitis	pos		+
41	19	Posterior uveitis	neg
42	69	Recurrent anterior uveitis, Posner Schlossman	pos		+				yes
43	38	Acute anterior uveitis	neg
44	49	Recurrent anterior uveitis, Posner Schlossman	pos	+
45	43	Posterior uveitis	pos					+

Demonstrates the patient cohort demographics which included 28 men and 17 women with a mean age of 43 years. Aqueous humor of 22 patients was PCR positive for either CMV, HSV, VZV, EBV or Toxoplasma gondii. 5 patients were tested multiple times, indicated by a *. 3 patients were PCR positive for two infectious agents, indicated by a **. Potentially false positive results are noted in parenthesis

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ISSN: 1471-2415

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