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Fig. 7 | BMC Ophthalmology

Fig. 7

From: Effect of bradykinin on TGF-β1-induced retinal pigment epithelial cell proliferation and extracellular matrix secretion

Fig. 7

a Effect of BK on TGF-β1-induced Akt phosphorylation in RPE cells. a TGF-β1 facilitated significant increases in Akt phosphorylation levels in treated RPE cells compared to control cells; however, this effect was inhibited via incubation with BK before TGF-β1 treatment but could be blocked by HOE-140. b Neither BK nor HOE-140 had an effect on TGF-β1-induced Erk1/2 phosphorylation. *P < 0.05 versus without addition, && P < 0.01 versus with TGF-β1 alone. ####P < 0.0001 versus with BK and TGF-β1

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BMC Ophthalmology

ISSN: 1471-2415

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