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Table 3 Test performance characteristics of included studies

From: Colour Doppler analysis of ophthalmic vessels in the diagnosis of carotic artery and retinal vein occlusion, diabetic retinopathy and glaucoma: systematic review of test accuracy studies

Name, year

Vessel

Pathology

TP

FP

FN

TN

Sensitivity

Specificity

negative LR (95% CI)

positive LR (95% CI)

Han-Hwa Hu, 1993 [10]

oaa

0

21

20

4

87

85.70%

80.90%

0.197 (0.080 to 0.485)

4.49 (2.92 to 6.91)

Jimenez-Aragon, 2013 [14]

oa

2

7

6

5

53

54.60%

90.00%

0.464 (0.236 to 0.911)

5.74 (2.34 to 14.06)

Martinez, 2005 [15]

oa

2

19

2

4

24

82.60%

92.30%

0.188 (0.077 to 0.462)

10.74 (2.80 to 41.21)

Suprasanna, 2014 [16]

oa

2

24

9

1

44

96.00%

83.00%

0.048 (0.007 to 0.330)

5.65 (3.10 to 10.31)

Basturk, 2012 [13]

oa

1

40

20

11

47

78.40%

70.00%

0.307 (0.178 to 0.531)

2.63 (1.77 to 3.90)

Paivansalo, 1999 [11]

oa

0

13

2

35

44

27.00%

96.00%

0.762 (0.635 to 0.915)

6.23 (1.49 to 26.10)

Arai, 1998 [12]

oa

1

14

8

11

19

56.00%

72.00%

0.625 (0.377 to 1.037)

1.89 (0.96 to 3.72)

Jimenez-Aragon, 2013 [14]

craa

2

6

4

6

55

50.00%

94.00%

0.536 (0.303 to 0.948)

7.38 (2.45 to 22.21)

Arai, 1998 [12]

cra

1

16

10

9

17

64.00%

63.00%

0.572 (0.315 to 1.039)

1.73 (0.97 to 3.06)

Han-Hwa Hu, 1993 [10]

cra

0

21

11

4

96

84.00%

89.60%

0.178 (0.072 to 0.439)

8.17 (4.55 to 14.67)

Paivansalo, 1999 [11]

cra

0

15

6

33

40

31.00%

88.00%

0.791 (0.634 to 0.986)

2.4 (1.02 to 5.64)

Arsène, 2002 [18]

cra

3

48

11

21

22

70.00%

66.00%

0.457 (0.297 to 0.702)

2.09 (1.26 to 3.47)

Plange, 1999 [17]

cra

2

30

4

32

36

48.40%

90.00%

0.573 (0.441 to 0.745)

4.84 (1.84 to 12.70)

Tranquart, 1999 [19]

crva

3

12

18

6

33

67.00%

65.00%

0.515 (0.260 to 1.021)

1.89 (1.15 to 3.10)

Williamson, 1994 [6]

crv

3

6

3

2

19

75.00%

86.00%

0.289 (0.086 to 0.972)

5.5 (1.79 to 16.94)

  1. TP true positives, FP false positives, FN false negatives, TN true negatives, LR likelihood ratio, CI confidence interval
  2. aoa ophthalmic artery, cra central retinal artery, crv central retinal vein
  3. Pathology: 0 = central carotic stenosis; 1 = diabetes; 2 = glaucoma; 3 = central retinal vein occlusion