Comparison of the acute ocular manifestations of Stevens-Johnson syndrome and toxic epidermal necrolysis in Chinese eyes: a 15-year retrospective study

Table 2 This table shows the severity of ocular involvement during the acute phase in the two groups. The grading system was based on that described by Power et al. [16] There was a statistical significant difference between the degree of ocular involvement in the two groups (0.022). Post-hoc analysis showed that the TEN group had significantly more mild involvement cases than the SJS or SJS/TEN overlap group (p = 0.01), while in all other groups, no statistically significant differences were found (p > 0.05)

Ocular involvement	Stevens-Johnson syndrome and SJS/TEN overlap	Toxic epidermal necrolysis
None	12 (60%)	3 (25%)
Mild^a	1 (5%)	5 (42%)
Moderate^b	3 (15%)	0 (0%)
Severe^c	4 (20%)	4 (33%)

^aMild involvement: lid edema, eyelid skin involvement including denudation and desquamation, mild corneal involvement (punctate fluorescein staining), mild conjunctival injection or chemosis only
^bModerate involvement: membranous conjunctivitis, corneal epithelial defects with more than 30% healing with medical treatment, corneal ulceration or corneal infiltrates
^cSevere involvement: symblepharon formation, acquired eyelid malpositions, non-healing corneal epithelial defects, visual loss or conjunctival fornix foreshortening

ISSN: 1471-2415