Serum uric acid concentration is associated with hypertensive retinopathy in hypertensive chinese adults

BMC Ophthalmology

Table 4 Stratified analysis of the association of SUA on the risk of hypertensive retinopathy (SUA as a continuous variable)

	n	Events	%	Model 1		Model 2		P value for interaction
	n	Events	%	OR (95% CI)	P	OR (95% CI)	P	P value for interaction
Gender								0.122
Male	5206	4056	77.91	1.07 (1.02, 1.11)	0.005	1.02 (0.96, 1.07)	0.593
Female	7760	5792	74.64	1.10 (1.06, 1.15)	<0.001	1.09 (1.04, 1.14)	<0.001
Age (years)								0.129
< 60	8846	6759	76.41	1.14 (1.08, 1.20)	<0.001	1.11 (1.04, 1.18)	0.002
≥ 60	4120	3089	74.98	1.08 (1.04, 1.11)	<0.001	1.03 (0.99, 1.08)	0.154
Treatment Group								0.267
Enalapril only	6531	4960	75.95	1.08 (1.04, 1.12)	<0.001	1.05 (1.00, 1.10)	0.076
Enalapril-Folic Acid	6435	4888	75.96	1.11 (1.07, 1.16)	<0.001	1.07 (1.02, 1.13)	0.010
SBP (mmHg)								0.535
< 127.0	4163	3088	74.18	1.11 (1.06, 1.16)	<0.001	1.08 (1.01, 1.14)	0.019
127.0 ≤ SBP < 141.3	4204	3197	76.05	1.12 (1.07, 1.18)	<0.001	1.09 (1.03, 1.16)	0.006
≥ 141.3	4448	3447	77.5	1.07 (1.02, 1.12)	0.008	1.01 (0.95, 1.07)	0.846
DBP (mmHg)								0.083
< 78.0	4145	3071	74.09	1.10 (1.05, 1.15)	<0.001	1.06 (1.00, 1.12)	0.069
≥ 78.0, <86.5	4392	3303	75.2	1.14 (1.08, 1.20)	<0.001	1.09 (1.03, 1.16)	0.005
≥ 86.5	4278	3358	78.49	1.05 (0.99, 1.10)	0.083	1.02 (0.95, 1.08)	0.618
DM								0.834
No	10,089	7623	75.56	1.10 (1.07, 1.14)	<0.001	1.05 (1.01, 1.09)	0.028
Yes	2412	1857	76.99	1.09 (1.02, 1.15)	0.009	1.07 (0.99, 1.16)	0.077

Abbreviations: SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, DM diabetes mellitus, Treatment Group Enalapril only, Enalapril-Folic Acid
Binary logistic regression models evaluating the association of serum uric acid(SUA) with hypertensive retinopathy(HR). CI confidence interval, OR odds ratio
Model 1: unadjusted
Model 2: adjusted for age, sex, study center, treatment group, body mass index(BMI), SBP, DBP, creatinine, triglycerides, and fasting plasma glucose if not stratified

ISSN: 1471-2415