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Table 2 Meta-analysis of associations between IL23R polymorphisms and overall uveitis

From: The association between genetic polymorphisms of the interleukin-23 receptor gene and susceptibility to uveitis: a meta-analysis

Polymorphism

 

Test of association

 

Test of heterogeneity

  

OR

95% CI

P-value

Model

P-value

I2(%)

rs7517847

G vs. T

1.01

0.92–1.12

0.83

F

0.14

40

GG vs. GT + TT

0.70

0.40–1.21

0.20

R

0.00003

81

GG + GT vs. TT

0.92

0.80–1.07

0.29

F

0.20

32

GG vs. TT

0.88

0.65–1.19

0.41

R

0.06

53

rs17375018

A vs. G

0.68

0.47–0.99

0.05

R

<0.00001

87

AA vs. AG + GG

0.76

0.49–1.18

0.22

R

0.09

50

AA + AG vs. GG

0.59

0.35–0.99

0.04

R

<0.00001

88

AA vs. GG

0.56

0.29–1.09

0.09

R

0.003

75

rs11209032

A vs. G

1.20

0.87–1.64

0.27

R

<0.0001

86

AA vs. AG + GG

1.33

1.11–1.60

0.002

F

0.07

54

AA + AG vs. GG

1.13

0.82–1.56

0.45

R

0.03

64

AA vs. GG

1.34

0.85–2.12

0.20

R

0.007

71

  1. R random effects model, F fixed effects model
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