Table 5 Differentially expressed genes enriched in steroid biosynthesis
From: Identification of pathogenic genes and upstream regulators in age-related macular degeneration
Symbol | Gene annotation | Enzyme | Up down |
|---|---|---|---|
DHCR7 | delta 7-dehydrocholesterol reductase | EC:1.3.1.21 | Up |
FDFT1 | Farnesyl-DiphosphateFarnesyltransferase 1. | EC:2.5.1.21 | Up |
CYP27B1 | cytochrome P450 family 27 subfamily B member 1 | EC:1.14.13.13 | Up |
TM7SF2 | transmembrane 7 superfamily member 2 | EC:1.3.1.70 | Up |
SQLE | squaleneepoxidase | EC:1.14.14.17 | Up |
SOAT2 | sterol O-acyltransferase 2 | EC:2.3.1.26 | Down |