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Table 2 Levels of cytokines in aqueous humor

From: Assessment of biomarkers using multiplex assays in aqueous humor of patients with diabetic retinopathy

 

DR

NDR

Control

p

IL-1ra

95.60 ± 93.12

120.71 ± 120.37

88.12 ± 107.15

0.643

IL-1β

1.07 ± 1.03

1.28 ± 1.61

1.86 ± 1.96

0.409

IL-1α

0.88 ± 0.38

1.26 ± 0.24

1.42 ± 0.31

<0.001*

IL-2

17.12 ± 13.07

16.66 ± 16.26

17.40 ± 18.35

0.991

IL-4

6.50 ± 3.38

10.17 ± 3.60

11.98 ± 3.77

<0.001*

IL-5

1.77 ± 0.98

1.74 ± 1.53

2.45 ± 1.68

0.292

IL-6

40.64 ± 16.52

32.46 ± 6.76

23.00 ± 14.42

<0.001*

IL-7

5.00 ± 2.38

4.05 ± 1.46

3.72 ± 1.26

0.143

IL-8

42.20 ± 33.03

23.60 ± 6.84

27.75 ± 5.58

0.011*

IL-9

67.92 ± 49.21

127.35 ± 30.46

152.58 ± 28.84

<0.001*

IL-10

0.24 ± 0.16

0.16 ± 0.20

0.24 ± 0.28

0.495

IL-12p70

0.30 ± 0.23

0.35 ± 0.51

0.47 ± 0.50

0.621

IL-13

4.46 ± 1.88

5.80 ± 3.38

7.33 ± 3.33

0.083

IL-15

14.42 ± 4.40

14.12 ± 8.20

17.45 ± 6.89

0.298

IL-17A

0.94 ± 0.53

0.98 ± 0.80

1.11 ± 0.82

0.828

IL-18

1.28 ± 0.96

0.81 ± 1.49

1.43 ± 1.71

0.470

IL-21

6.52 ± 4.59

12.77 ± 4.81

16.89 ± 6.91

<0.001*

IL-22

183.16 ± 115.29

188.33 ± 133.86

253.94 ± 170.78

0.307

IL-23

24.23 ± 14.56

46.50 ± 10.82

57.02 ± 12.46

<0.001*

IL-27

19.82 ± 13.71

31.78 ± 14.88

37.41 ± 8.39

<0.001*

IL-31

27.90 ± 17.32

52.73 ± 13.14

60.99 ± 14.53

<0.001*

TNFα

4.04 ± 1.83

3.53 ± 1.74

3.77 ± 2.57

0.840

TNFβ/LTA

14.20 ± 10.19

26.94 ± 5.90

36.70 ± 6.44

<0.001*

IFNγ

 

IFNα

0.75 ± 0.30

1.04 ± 0.29

1.13 ± 0.31

0.001*

GM-CSF

25.98 ± 10.31

25.18 ± 13.41

26.75 ± 14.96

0.937

BDNF

1.83 ± 1.24

2.64 ± 0.92

2.81 ± 0.94

0.055

LIF

10.89 ± 9.04

2.86 ± 2.18

2.70 ± 1.35

<0.001*

SCF

5.93 ± 3.82

3.72 ± 2.58

4.38 ± 2.74

0.184

  1. Data are expressed as the mean ± SD (pg/ml)
  2. IL interleukin, TNF tumour necrosis factor, IFNγ interferon-γ, GM-CSF granulocyte-macrophage colony stimulating factor, BDNF brain derived neurotrophic factor, LIF leukaemia inhibitor factor, SCF stem cell factor
  3. * p < 0.05