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Table 5 Increased aqueous cytokine concentrations in patients with or without diabetic macular edema

From: Assessment of biomarkers using multiplex assays in aqueous humor of patients with diabetic retinopathy

Cytokine

DME (n = 55)

Non-DME (n = 46)

P

IL-6

50.65 ± 6.31

29.11 ± 13.40

<0.001*

IL-8

62.04 ± 17.65

36.38 ± 16.76

<0.001*

IP-10

54.43 ± 10.83

32.06 ± 11.67

<0.001*

LIF

13.81 ± 4.19

6.57 ± 3.46

<0.001*

HGF

1513.58 ± 183.90

814.42 ± 326.57

<0.001*

VEGF-A

445.40 ± 88.86

326.91 ± 61.29

<0.001*

  1. Data are expressed as the mean ± SD (pg/ml)
  2. DME diabetic macular edema, IL interleukin, IP interferon inducibleprotein, LIF leukaemia inhibitor factor, HGF hepatocyte growth factor, VEGF vascular endothelial growth factor
  3. * p < 0.05
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BMC Ophthalmology

ISSN: 1471-2415

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