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Table 1 Ocular manifestations and outcomes of antiviral therapy of 12 patients with CMV retinitis

From: High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation

No.

Involved eye

Presenting VA (LogMAR)

Involved zone

Sizes of lesions

KP

Anterior chamber inflammation

Vitritis

CMV peak in the blood

CMV copies in vitreous

No. of IVTG

Final VA (LogMAR)

Outcomes

1

OD

+0.1

3

<10%

Yes

Yes

Yes

7.3 × 103

undetectable

8

0.0

Improvement

 

OS

+0.1

3

<10%

No

Yes

Yes

 

undetectable

17

0.0

Improvement

2

OD

+2.6

1,2,3

>50%

No

No

No

1.9 × 105

7.23 × 104

13

+1.0

Stabilization

 

OS

+2.6

1,2,3

>50%

No

No

No

 

8.65 × 103

13

+1.0

Improvement

3

OD

+0.2

3

<10%

No

No

No

2.78 × 106

undetectable

2

+0.1

Stabilization

4

OD

+0.2

1,2,3

>50%

No

No

Yes

2.4 × 104

1.00 × 106

25

+1.0

Deterioration

 

OS

+0.1

1,2

10%–50%

No

No

Yes

 

2.34 × 105

13

+0.4

Deterioration

5

OD

+0.1

1

<10%

No

No

No

1.0 × 104

5.52 × 102

7

−0.1

Improvement

 

OS

+0.1

2

<10%

Yes

Yes

Yes

 

5.63 × 102

21

0.0

Improvement

6

OD

0.0

3

<10%

No

No

Yes

4.4 × 103

undetectable

4

0.0

Stabilization

7

OS

0.0

3

<10%

Yes

Yes

Yes

9.0 × 103

5.34 × 102

4

0.0

Stabilization

8

OD

+0.4

1,2,3

>50%

No

No

No

 

3.32 × 106

28

+2.9

Deterioration

 

OS

+0.5

1,2,3

>50%

No

No

No

 

3.68 × 106

29

+2.9

Deterioration

9

OS

+0.3

1,2

10%–50%

No

No

No

3.5 × 103

6.79 × 103

9

+0.1

Improvement

10

OS

+0.2

2

10%–50%

No

No

No

 

6.24 × 102

3

+0.2

Stabilization

11

OD

+0.1

3

<10%

No

No

No

4.4 × 104

4.18 × 104

8

+0.5

Deterioration

 

OS

+0.2

2,3

10%–50%

Yes

Yes

Yes

 

1.85 × 105

8

+2.6

Deterioration

12

OD

+1.0

1,2,3

>50%

No

No

Yes

3.3 × 103

2.79 × 106

17

+2.7

Deterioration

 

OS

+0.2

1,2,3

>50%

No

No

Yes

 

2.24 × 106

17

+2.6

Deterioration

  1. VA: visual acuity; Presenting VA: vision acuity of the involved eye when CMV retinitis was first diagnosed; Final VA: vision acuity at the last visit; KP: keratic precipitates; OU: both eyes; OD: right eye; OS: left eye; involved zone of retinal lesions: zone 1 was in the area within 1500 μm of the optic nerve or within 3000 μm of the fovea, zone 2 was located from the edge of zone 1 anteriorly to the vortex veins and zone 3 was located anteriorly from zone 2 to the ora serrata. Sizes of lesions were classified as involving <10%, 10% to 50%, or >50% of the total retinal area based on the fundus photograph. Patient numbers correspond to those in Table 1