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Table 1 Characteristics of the studies included in this review

From: Efficacy and safety of transepithelial corneal collagen crosslinking surgery versus standard corneal collagen crosslinking surgery for keratoconus: a meta-analysis of randomized controlled trials

Author

Year

Country

Design

Follow-up (months)

Intervention

No. of eyes

Age(years)

∆Kmax (D)

∆CDVA (logMAR)

∆Corneal thickness (μm)

Soeters, N

2015

Netherlands

Randomized Controlled Trial

12

Standard CXL

24

24(18–44)

-1.5 ± 2.0

-0.07 ± 0.21

−4 ± 8

     

Transepethelial CXL

33

24(18–48)

0.3 ± 1.8

−0.14 ± 0.21

0 ± 12

Bikbova, G

2016

Russia

Randomized Controlled Trial

24

Standard CXL

73

30(18–42)

−1.89 ± 3.023

−0.02 ± 0.2793

−13 ± 37.2252

     

Transepethelial CXL

76

28(18–44)

−0.74 ± 3.0494

−0.07 ± 0.4525

−6.72 ± 38.61118

Lombardo, M

2017

Italy

Randomized Controlled Trial

12

Standard CXL

12

29.4 ± 5.6

−0.82 ± 1.20

−0.03 ± 0.06

−1 ± 494.60

     

Transepethelial CXL

22

31.0 ± 6.6

−0.52 ± 1.30

−0.10 ± 0.12

9 ± 489.81