Fig. 1
From: Longitudinal observation of subretinal fibrosis in Vogt-Koyanagi-Harada disease
Longitudinal documentation of optical coherence tomography (OCT) and fundus photography: patient 1. Subretinal fibrosis (SRF) was barely detectable (a, b) until at day 44 of disease course (c), which appear as a pigmented subretinal membrane on fundus photograph and a hyper-reflective layer above the retinal pigment epithelium (RPE) on OCT (c). SRF then underwent shape-change/migration and proliferation/pigmentation under the subretinal space (d, e), and then stabilized (f). De-pigmentation of SRF along with the whole fundus ensued thereafter (g, h), followed by re-pigmentation of SRF (i, j). Macular edema was detected at 10 months of disease course (h) and responded well to sub-conjunctival injection of triamcinolone acetonide