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Table 2 Reported cases of infectious scleritis after posterior subtenon triamcinolone acetonide injection

From: Scedosporium apiospermum infectious scleritis following posterior subtenon triamcinolone acetonide injection: a case report and literature review

Patient

Reported year

Age and gender

Comorbidities (focal and systemic)

Durations from STTA

Symptoms at onset

Clinical ocular findings at onset

Causative pathogen

Pharmacotherapy (topical)

Pharmacotherapy (systemic)

Surgical therapy (except incision of abscess)

Recurrence

Outcome/final VA (decimal)

Reference

1

2004

90, female

BRVO

3 weeks

Orbital mass

Orbital mass, blepharoptosis

Staphylococcus aureus

None

Clindamycin

None

 

Recovery/NA

Engelman et al. [14]

2

2007

63, male

Graves’ ophthalmopathy

3 months

None

Subconjunctival abscess, anterior chamber cell, retinal white lesion and RD

Alternaria spp.

Fluconazole, miconazole, micafungin

Fluconazole, miconazole

Cataract extraction, PPV, scleral buckling

+

Recovery/0.7

Isshiki et al. [12]

3

2007

50, male

Uveoretinitis, Bechet’s disease, diabetes

2 weeks

Discharge

Subconjunctival whitish mass

Nocardia spp.

levofloxacin, cefmenoxime

Minocycline

None

+

Recovery/NA

Kusaka et al. [11]

4

2007

62, female

Diabetic retinopathy

2 month

Ocular pain

Periocular mass, conjunctival injection, anterior chamber cell

Pseudallescheria boydii

Amphotericin B, itraconazole

Amphotericin B, itraconazole

Debridement of subtenon abscess

 

Phthisis bulbi/NA

Oh et al. [10]

5

2007

33, female

Intermediate uveitis

2 weeks

Pain, redness and yellow discharge

Subconjunctival infiltrate

Streptococcus pneumoniae

ciprofloxacin

ciprofloxacin

None

+

Recovery/1.2

Azarbod et al. [13]

6

2008

80, female

CME after cataract surgery, POAG

A few weeks

Pain, red eye

Scleral necrosis, scleral thinning, nonrhegmatogenous RD

Nocardia asteroids

Amikacin, ceftazidime, trimethoprim sulfate, polymyxin B

Minocycline

Bovine endocardium patch graft

 

Recovery/CF

Seth et al. [9]

7

2009

58, male

Diabetic retinopathy

3 months

Diplopia, deep ocular pain

Ptosis, restricted eye movement, epibulbar abscess

Scedosporium apiospermum

Gatifloxacin, natamycin

Levofloxacin, itraconazole, voriconazole

PPV, cataract extraction

 

Recovery/0.5

Ikewaki et al. [8]

8

2011

20, male

Corneal graft rejection

2 days

Ocular pain, ocular discharge

Corneal edema, anterior chamber reaction, mucoid discharge, localized conjunctival necrosis

Staphylococcus epidermidis

Amikacin, vancomycin

Ciprofloxacin

None

 

Recovery/NA

Gharaee et al. [7]

9

2017

75, male

BRVO, hypertension, colon cancer and metastatic hepatic tumor

2 months

Ocular pain, hyperemia

Subtenon abscess, lid swelling, anterior chamber cells

Scedosporium apiospermum sensu stricto

Voriconazole, levofloxacin, natamycin

Voriconazole

Debridement of infected sclera

+

Recovery/0.2

This study

  1. STTA subtenon triamcinolone acetonide, VA visual acuity, BRVO branch retinal vein occlusion, NA not applicable, RD retinal detachment, PPV pars plana vitrectomy, CME cystoid macular edema, POAG primary open angle glaucoma, CF counting fingers