The function and morphology of Meibomian glands in patients with thyroid eye disease: a preliminary study

BMC Ophthalmology

Table 2 Comparison between active and inactive thyroid eye diseases

	Active TED^† (11 eyes of 6 patients)	Inactive TED^‡ (20 eyes of 11 patients)	P value^§
Age (yr)	45.2 ± 16.1	44.4 ± 7.3	0.679
Sex (female: male)	7: 4	11: 9	0.718
Disease duration (months)	80.8 ± 96.8	28.9 ± 20.5	0.264
Exophthalmos (mm)	23.1 ± 4.3	18.5 ± 3.3	0.005^*
Lagophthalmos (mm)	2.13 ± 2.67	0.18 ± 0.59	< 0.001^*
Partial blinking rate (%)	58.2 ± 29.9	58.5 ± 37.8	0.834
ST-1 (mm)	9.2 ± 5.6	14.5 ± 10.0	0.199
SPEED (score)	7.1 ± 4.6	7.6 ± 3.9	0.803
MG dysfunction signs^# (no. of eyes; %)	11 (100%)	16 (80%)	0.269
MGd (score)	2.5 ± 0.9	1.8 ± 0.7	0.03^*
MGE (score)	0.2 ± 0.4	0.9 ± 1.2	0.148
MGYLS (score)	5.4 ± 2.9	4.3 ± 3.1	0.362
TMQS (score)	8.2 ± 5.5	11.2 ± 9.0	0.482
LLT (nm)	86.3 ± 18.0	67.4 ± 21.0	0.024^*

^†,‡Patients with thyroid eye diseases (TED) were classified by the clinical activity score (CAS) as having active TED (CAS 2−3) or inactive TED (CAS 0−1); ^§Fisher’s exact test was used to test the between-group differences in sex and MG dysfunction signs, while Wilcoxon’s rank-sum test was used to test other parameters. (^*)Statistically significant (P < 0.05)
^#MG dysfunction signs, signs of meibomian gland (MG) dysfunction, including irregular lid margin, vascular engorgement, plugged meibomian gland orifices, and displacement of mucocutaneous junction

ISSN: 1471-2415