Association between blood pressure and retinal arteriolar and venular diameters in Chinese early adolescent children, and whether the association has gender difference: a cross-sectional study

He, Yuan; Li, Shi-Ming; Kang, Meng-Tian; Liu, Luo-Ru; Li, He; Wei, Shi-Fei; Ran, An-Ran; Wang, Ningli

doi:10.1186/s12886-018-0799-x

Table 6 Subgroup analysis stratified by potential effect modifiers of AVR with BP, stratified by potential modifiers

From: Association between blood pressure and retinal arteriolar and venular diameters in Chinese early adolescent children, and whether the association has gender difference: a cross-sectional study

Potential Effect Modifiers			n	AVR
				Model 1	p	Model 2	P
SBP	Age	10 + 11	70	−0.010 ± 0.006	0.118	−0.007 ± 0.007	0.37
		12	1122	−0.010 ± 0.002	<.001	−0.007 ± 0.002	<.001
		13 + 14 + 15	309	−0.010 ± 0.003	0.002	−0.007 ± 0.004	0.05
	Sex	Male	792	−0.010 ± 0.002	<.001	−0.009 ± 0.002	<.001
	Sex	Female	709	−0.009 ± 0.006	<.001	−0.006 ± 0.002	0.02
	BMI	Upper 50%	750	−0.006 ± 0.002	0.020	−0.005 ± 0.002	0.06
	BMI	Lower 50%	751	−0.010 ± 0.002	<.001	−0.010 ± 0.002	<.001
	Birth weight	Upper 50%	778	−0.010 ± 0.002	<.001	−0.007 ± 0.002	0.001
	Birth weight	Lower 50%	723	−0.010 ± 0.002	<.001	−0.007 ± 0.002	0.002
	Gestational age	Term	1372	−0.010 ± 0.002	<.001	−0.007 ± 0.001	<.001
	Gestational age	Preterm	129	−0.010 ± 0.004	0.035	−0.008 ± 0.007	0.015
DBP	Age	10 + 11	70	−0.016 ± 0.008	0.046	−0.009 ± 0.009	0.314
		12	1122	−0.015 ± 0.002	<.001	−0.013 ± 0.002	<.001
		13 + 14 + 15	309	−0.007 ± 0.005	0.136	−0.003 ± 0.004	0.493
	Sex	Male	792	−0.016 ± 0.003	<.001	−0.014 ± 0.003	<.001
	Sex	Female	709	−0.011 ± 0.006	0.003	−0.009 ± 0.003	0.009
	BMI	Upper 50%	750	−0.011 ± 0.003	<.001	−0.011 ± 0.003	<.001
	BMI	Lower 50%	751	−0.012 ± 0.003	<.001	−0.012 ± 0.003	<.001
	Birth weight	Upper 50%	778	−0.013 ± 0.019	<.001	−0.011 ± 0.003	<.001
	Birth weight	Lower 50%	723	−0.013 ± 0.003	<.001	−0.012 ± 0.003	<.001
	Gestational age	Term	1372	−0.013 ± 0.002	<.001	−0.011 ± 0.002	<.001
	Gestational age	Preterm	129	−0.015 ± 0.007	0.03	−0.012 ± 0.007	0.137
MABP	Age	10 + 11	70	−0.016 ± 0.008	0.048	−0.009 ± 0.009	0.302
		12	1122	−0.015 ± 0.002	<.001	−0.013 ± 0.002	<.001
		13 + 14 + 15	309	−0.010 ± 0.005	0.02	−0.006 ± 0.005	0.192
	Sex	Male	792	−0.016 ± 0.002	<.001	−0.014 ± 0.002	<.001
	Sex	Female	709	−0.013 ± 0.003	<.001	−0.009 ± 0.003	0.005
	BMI	Upper 50%	750	−0.010 ± 0.003	<.001	−0.010 ± 0.003	0.002
	BMI	Lower 50%	751	−0.014 ± 0.003	<.001	−0.012 ± 0.003	<.001
	Birth weight	Upper 50%	778	−0.015 ± 0.003	<.001	−0.012 ± 0.003	<.001
	Birth weight	Lower 50%	723	−0.014 ± 0.003	<.001	−0.007 ± 0.007	<.001
	Gestational age	Term	1372	−0.014 ± 0.002	<.001	−0.012 ± 0.002	<.001
	Gestational age	Preterm	129	−0.016 ± 0.006	0.018	−0.012 ± 0.007	0.108

Model 1:unadjusted model; Model 2: adjusted for age, gender, axial length, BMI, waist, spherical equivalent, birth weight and gestational age. SBP systolic blood pressure, DBP diastolic blood pressure, MABP mean arterial blood pressure, AVR arteriolar to venular ratio. Term means pregnancy lasts longer than 37 weeks, and preterm represents that the duration of pregnancy is less than 37 weeks.Significant p values are bolded

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