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Table 1 Demographic characteristics of the hemodialysis group (pre HD) and the control group: comparison of basic situation and baseline data (Mean ± SD)

From: Ocular changes during hemodialysis in patients with end-stage renal disease

Pre HD

HD Group

Control Group

P value

Male [eyes (percentage)]

54 (60.00%)

60 (63.83%)

0.593

Female [eyes (percentage)]

36 (40.00%)

34 (36.17%)

Age (year)

57.78 ± 13.57

54.90 ± 17.60

0.239

Systolic pressure (mmHg)

147.14 ± 22.43

133.65 ± 18.64

0.016*

Diastolic pressure (mmHg)

83.75 ± 16.03

75.28 ± 11.79

0.022*

Urea (mmol/L)

24.330 ± 7.853

5.275 ± 0.936

< 0.001**

Creatinine (umol/L)

891.10 ± 70.78

77.00 ± 20.38

< 0.001**

Uric acid (umol/L)

427.50 ± 79.78

367.88 ± 85.441

0.012*

Na (mmol/L)

138.20 ± 2.64

142.00 ± 2.45

< 0.001**

K (mmol/L)

4.860 ± 0.920

4.191 ± 0.217

< 0.001**

Ca (mmol/L)

2.279 ± 0.206

2.283 ± 0.070

0.908

P (mmol/L)

1.849 ± 0.542

1.160 ± 0.180

< 0.001**

Mg (mmol/L)

1.050 ± 0.129

0.873 ± 0.035

< 0.001**

PTH (ng/L)

479.70 ± 419.20

40.30 ± 12.45

< 0.001**

Fasting plasma glucose (mmol/L)

7.725 ± 3.356

5.433 ± 0.695

< 0.001**

Spherical power (D)

0.088 ± 0.508

−2.4011 ± 3.7786

0.012*

Cylinder power (D)

−0.857 ± 0.138

−0.6711 ± 0.6071

0.070

logMAR of BCVA

0.100 ± 0.0282

− 0.0205 ± 0.2344

0.345

TBUT(s)

6.957 ± 0.861

9.171 ± 5.801

0.949

Schirmer’s I test (mm)

12.014 ± 2.020

16.934 ± 9.617

0.309

IOP (mmHg)

12.855 ± 0.420

15.01 ± 3.69

0.073

ACD (mm)

2.642 ± 0.073

2.783 ± 0.481

0.082

CT (μm)

575.18 ± 5.859

549.11 ± 38.67

0.650

ECD (cell/mm2)

2758.47 ± 35.494

2707.46 ± 194.91

0.055

ECS (μm2)

363.16 ± 6.577

371.34 ± 29.27

0.132

ECSCV

40.717 ± 1.573

40.88 ± 7.35

0.381

LT (mm)

4.146 ± 0.064

3.979 ± 0.460

0.120

CSF (μm)

244.36 ± 4.464

249.68 ± 32.75

0.080

SIM (μm)

312.22 ± 2.912

323.45 ± 22.49

0.350

NIM (μm)

310.28 ± 2.904

322.13 ± 21.33

0.220

IIM (μm)

311.14 ± 3.990

316.29 ± 17.85

0.022*

TIM (μm)

302.88 ± 4.233

310.79 ± 19.39

0.030*

SOM (μm)

276.82 ± 3.915

280.42 ± 16.98

0.475

NOM (μm)

289.25 ± 2.368

294.61 ± 19.35

0.428

IOM (μm)

267.27 ± 5.037

266.45 ± 19.31

0.204

TOM (μm)

259.62 ± 5.432

262.37 ± 20.73

0.290

Average RT (μm)

273.40 ± 3.302

276.39 ± 17.37

0.164

RNFL thickness (μm)

90.65 ± 1.829

96.24 ± 23.06

0.669

CHT (μm)

289.55 ± 11.385

232.87 ± 65.23

0.302

  1. PTH Parathyroid hormone, TBUT Tear break-up time, logMAR Logarithmic minimum angle of resolution, BCVA Best corrected visual acuity, IOP Intraocular pressure, ACD Anterior chamber depth, LT Lens thickness, CT Corneal thickness, ECD Endothelial cell density, ECS Endothelial cell size, ECSCV Endothelial cell size variation coefficient, CSF Central subfield, SIM Superior inner macula, NIM Nasal inner macula, IIM Inferior inner macula, TIM Temporal inner macula, SOM Superior outer macula, NOM Nasal outer macula, IOM Inferior outer macula, TOM Temporal outer macula, MV Macular volume, RNFL Retinal nerve fiber layer, CHT Choroidal thickness, *: P <  0.05; **: P<0.01