Fig. 2

Results of autologous retinal graft and blood clot in a 55-year-old refractory macular hole patient. Despite 4 pars plana vitrectomies with ILM peeling and additional 5 gas-fluid exchanges, spectral domain optical coherence tomography images (SD-OCT) showed the hole persisting (a). The base diameter of the MH before the retinal graft transplantation was 576 μm, and the minimum opening of the MH size was 219 μm. After the procedure, the macular hole was successfully closed at 3 months (b) and 12 months (c). The fovea remained stable and the patient’s visual acuity improved from 20/1000 before the surgery to 20/100 at the final visit. SD-OCT imaging (d) and fundus photograph (e) obtained at 51 months postoperatively. SD-OCT showing partial restoration of external limiting membrane and gradually reconstructed ellipsoid zone (black arrowhead)