Table 1 Patients’ demographic and clinical characteristics by ITF severity level
Baseline characteristic | Overall (N = 158) | Dry eye severity level | ||
|---|---|---|---|---|
ITF 1 (n = 52) | ITF 2 (n = 54) | ITF 3/4 (n = 52) | ||
Age, mean (SD), y | 55 (16) | 53 (13) | 57 (17) | 56 (17) |
Female, n (%) | 130 (82) | 43 (83) | 41 (76) | 46 (88) |
White, n (%) | 136 (86) | 41 (79) | 47 (87) | 48 (92) |
Geographic region, n (%) | ||||
 Midwest | 7 (4) | 3 (6) | 4 (7) | 0 |
 Northeast | 37 (23) | 12 (23) | 12 (22) | 13 (25) |
 South | 80 (51) | 28 (54) | 28 (52) | 24 (46) |
 West | 34 (22) | 9 (17) | 0 (19) | 15 (29) |
Education level, n (%) | ||||
 High school or less | 38 (24) | 12 (23) | 12 (22) | 14 (27) |
 Some college or higher | 120 (76) | 40 (77) | 42 (78) | 38 (73) |
Employment status, n (%) | ||||
 Employed | 103 (65) | 36 (69) | 36 (67) | 31 (60) |
 Retired/disabled | 47 (30) | 12 (23) | 16 (30) | 19 (37) |
 Nonemployed | 8 (5) | 4 (8) | 2 (4) | 2 (4) |
Ocular comorbidity, n (%) | ||||
 Cataract | 48 (30) | 13 (25) | 16 (30) | 19 (37) |
 Primary open-angle glaucoma | 8 (5) | 3 (6) | 2 (4) | 3 (6) |
 Ocular hypertension | 2 (1) | 0 | 0 | 2 (4) |
 Sjögren’s syndrome | 4 (3) | 1 (2) | 1 (2) | 2 (4) |
 Ocular allergy | 2 (1) | 2 (4) | 0 | 0 |
Nonocular comorbidity, n (%) | ||||
 Hypertension | 55 (35) | 12 (23)* | 16 (30)* | 27 (52) |
 Hyperlipidemia | 37 (23) | 10 (19) | 9 (17)* | 18 (35) |
 Gastrointestinal disordersa | 20 (13) | 5 (12) | 16 (11) | 9 (17) |
 Diabetes | 17 (11) | 3 (6)* | 4 (7) | 10 (19) |
 Rheumatologic disease | 14 (9) | 3 (6) | 3 (6) | 8 (15) |
 Asthma | 11 (7) | 1 (2) | 7 (13) | 3 (6) |
 Peripheral vascular disease | 2 (1) | 1 (2) | 1 (2) | 0 |
 Congestive heart failure | 2 (1) | 0 | 1 (2) | 1 (2) |
 Angina | 2 (1) | 0 | 0 | 2 (4) |
 Other | 26 (16) | 7 (13) | 13 (24) | 6 (12) |