Dry eye symptoms and impact on vision-related function across International Task Force guidelines severity levels in the United States

Table 3 OSDI questionnaire scores

OSDI score, mean (SD)		Dry eye severity level			P value^a
OSDI score, mean (SD)	Overall (N = 158)	ITF 1 (n = 52)	ITF 2 (n = 54)	ITF 3/4 (n = 52)	P value^a
Overall	35.1 (22.6)	26.5 (20.0)*^,†	33.8 (17.5)^‡	44.9 (26.1)	< 0.0001
Symptoms domain	32.8 (22.2)	23.3 (18.1)*^,†	32.3 (17.2)^‡	42.7 (26.2)	< 0.0001
Visual-Related Function domain	32.8 (25.1)	26.8 (23.0)^†	28.6 (21.0)^‡	42.7 (28.2)	0.0013
Environmental Triggers domain	43.3 (30.1)	34.2 (27.7)^†	43.2 (29.1)	52.2 (33.0)	0.0107

*P < 0.05 compared with ITF level 2; ^†P ≤ 0.005 compared with ITF level 3/4; ^‡P < 0.05 compared with ITF level 3/4
^aComparison of scores across all ITF levels using general linear models adjusted for gender, ethnicity (overall, Symptoms domain), and hypertension
ITF International Task Force, OSDI Ocular Surface Disease Index, SD standard deviation

ISSN: 1471-2415