Association of Genes implicated in primary angle-closure Glaucoma and the ocular biometric parameters of anterior chamber depth and axial length in a northern Chinese population

Table 5 Association results between the target Loci, AL, and ACD

GENE	SNP	Minor allele	AL (22.92 ± 0.891; 20.01~ 25.51)^a			ACD (2.74 ± 0.474; 0.25~ 4.51)^a
GENE	SNP	Minor allele	β	SE	P	β	SE	P
ZNRF3	rs7290117	T	−0.169	0.055	0.002	−0.008	0.0312	0.808
ZNRF3	rs2179129	G	0.003	0.0313	0.925	0.001	0.0157	0.925
ZNRF3	rs4823006	G	−0.023	0.0317	0.461	0.007	0.0159	0.666
ZNRF3	rs3178915	A	0.025	0.0313	0.42	0.005	0.0161	0.74
HGF	rs5745718	T	−0.005	0.0417	0.912	0.011	0.0243	0.64
HGF	rs12536657	A	0.001	0.0415	0.978	0.01	0.0243	0.69
HGF	rs12540393	C	−0.027	0.0394	0.495	0.012	0.023	0.594
HGF	rs17427817	C	−0.026	0.0393	0.516	0.011	0.023	0.647
HGF	rs3735520	A	−0.018	0.0309	0.568	−0.024	0.0157	0.127
MFRP	rs2510143	A	−0.016	0.0432	0.714	0.012	0.0218	0.581
MFRP	rs36015759	A	0.04	0.0339	0.234	0.009	0.0195	0.654
MFRP	rs3814762	T	−0.014	0.0362	0.703	0.002	0.0202	0.918

^aNumbers in parentheses indicate the Mean ± SD and the range of measured values for AL or ACD β, per-allele effect in ACD/AL, SE standard error for ascertainment of β, P, P-value for association adjusting for age and sex

ISSN: 1471-2415