Fig. 1

Effect of tubacin on retinal morphologic changes after I/R injury. (a) Photomicrographs of retinal cross-sections. Five well-organized retinal layers: ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; and GCL, ganglion cell layer. Analysis of the overall retinal thickness includes ONL, OPL, INL, IPL, and GCL. Analysis of the cell body counts from the retinal ganglion cell layer (GCL) over 200-μm distances. (b, c) Expression of THY as detected by Western blotting and quantitative analyses. The data are presented as means ± SEM (n = 5–8 rats per group). *P < 0.05, **P < 0.01 vs. Sham group; ^#P < 0.05, ^##P < 0.01 vs. I/R-plus-vehicle