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Table 2 Clinical Characteristics of the Study Samples

From: Effects of ranibizumab (Lucentis®) and bevacizumab (Avastin®) on human corneal endothelial cells

 

ranibizumab (Lucentis®)

bevacizumab (Avastin®)

Endothelial Cell Density ECD [Cells/mm2]

 Before Treatment (Mean [Range])

2441 [1700;3200]

2234 [1700;2800]

 After Treatment 0 μg/ml (control)

1847

1644

 After Treatment 2.5 μg/ml

1511

1587

 After Treatment 25 μg/ml

1460

1417

 After Treatment 250 μg/ml

1715

1352

 Cell loss 0 μg/ml (control)

18.1%

15.8%

 Cell loss 2.5 μg/ml

22.5%

18.0%

 Cell loss 25 μg/ml

25.7%

25.8%

 Cell loss 250 μg/ml

24.2%

32.5%

 Corneal Area [mm2] (Mean)

75.0

67.0