Table 1 This table summarizes the patient characteristics for the three dystrophy groups and healthy controls
From: Contrast sensitivity deficits in patients with mutation-proven inherited retinal degenerations
Rod-cone dystrophy | Stargardt disease | Best disease | Controls | P value IRD vs control | |
|---|---|---|---|---|---|
N (%) | 12 (22.2%) | 3 (5.6%) | 2 (3.7%) | 18 (52.8%) | NA |
Age in years, mean (SD) | 36.6 (15.9) | 57.0 (13.7) | 33.5 (14.4) | 52.9 (11.6) | P < 0.02a |
Gender | |||||
Male, n (%) | 5 (41.7%) | 1 (33.3%) | 1 (50.0%) | 9, (47.3%) | P = 0.74b |
Female, n (%) | 7 (58.3%) | 2 (66.7%) | 1 (50.0%) | 10, (52.6%) | |
LogMAR visual acuity, Mean (SD) | 0.10 (0.09) | 0.18 (0.11) | 0.15 (0.17) | −0.10 (0.07) | P < 0.0001c |
Gene mutation, N (%) | USH2A, 4 (33%) | ABCA4 (100%) | BEST1 (100%) | NA | NA |
RP1, 2 (16.7%) | |||||
ABHD12, 1 (8.33%) | |||||
RPFF8, 1 (8.33%) | |||||
RHO, 1 (8.33%) | |||||
FLVCR1, 1 (8.33%) | |||||
EYS, 1 (8.33%) | |||||
RPPF31, 1 (8.33%) |