Contrast sensitivity deficits in patients with mutation-proven inherited retinal degenerations

BMC Ophthalmology

Table 2 This table summarizes the contrast sensitivity for the patient groups

	Controls	Rod-cone dystrophy	Best Disease	Stargardt Disease (STGD)	P-value dystrophy versus controls	P value STGD vs other IRD
AULCSF	1.58 (0.15)	1.27 (0.20)	1.23 (0.32)	0.61 (0.27)	P < 0.0001	P < 0.001
1.0cpd	1.67 (0.10)	1.50 (0.12)	1.46 (0.20)	1.19 (0.25)	P < 0.0001	0.179
1.5 cpd	1.73 (0.10)	1.56 (0.13)	1.50 (0.25)	1.10 (0.22)	P < 0.0001	P < 0.001
3.0 cpd	1.77 (0.10)	1.54 (0.16)	1.46 (0.29)	0.84 (0.22)	P < 0.0001	P < 0.0001
6.0 cpd	1.60 (0.17)	1.27 (0.24)	1.23 (0.34)	0.45 (0.36)	P < 0.0001	P < 0.0001
12.0 cpd	1.08 (0.25)	0.63 (0.31)	0.65 (0.37)	0.19 (0.38)	P < 0.0001	P = 0.04
18.0 cpd	0.60 (0.31)	0.16 (0.23)	0.22 (0.25)	0.08 (0.17)	P < 0.0001	P = 1.00

The means (standard deviations) for the AULCSF and contrast sensitivity at each spatial frequency in cycles per degree (cpd) are provided. P-values are from Wald test based on GEE model
AULCSF Area Under the Log Contrast Sensitivity Function
IRD Inherited retinal degeneration
STGD Stargardt disease
Cpd cycles per degree
GEE general estimating equations
This table summarizes the contrast sensitivity for the patient groups. The means (standard deviations) for the AULCSF and contrast sensitivity at each spatial frequency (in cpd) are provided. P-values are from Wald test based on GEE model

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