Two-year topographic and densitometric outcomes of accelerated (45 mW/cm2) transepithelial corneal cross-linking for keratoconus: a case-control study

Huang, Jinrong; Shen, Yang; Jian, Weijun; Xu, Haipeng; Li, Meiyan; Zhao, Jing; Zhou, Xingtao; Liao, Hongfei

doi:10.1186/s12886-018-0999-4

Table 2 Changes in Corneal Densitometry

From: Two-year topographic and densitometric outcomes of accelerated (45 mW/cm²) transepithelial corneal cross-linking for keratoconus: a case-control study

Locations	Pre-operation		6 months Post-operation		12 months Post-operation		24 months Post-operation		F^a	P
	(n = 25)		(n = 23)		(n = 23)		(n = 22)
	Mean ± SD	Range	Mean ± SD	Range	Mean ± SD	Range	Mean ± SD	Range
Anterior layer	25.28 ± 4.42	19.90 to 36.10	24.29 ± 4.08	18.70 to 38.10	22.90 ± 5.16	16.7 to 42.7	21.31 ± 3.86	16.90 to 36.20	19.302	< 0.001^b
(Φ 0–2 mm)	25.28 ± 4.42	19.90 to 36.10	24.29 ± 4.08	18.70 to 38.10	22.90 ± 5.16	16.7 to 42.7	21.31 ± 3.86	16.90 to 36.20	19.302	< 0.001^b
Anterior layer	21.66 ± 3.05	17.20 to 29.20	20.73 ± 2.31	17.00 to 26.40	19.38 ± 2.48	16.40 to 24.50	18.20 ± 1.82	15.30 to 22.20	34.316	< 0.001^b
(Φ 2–6 mm)	21.66 ± 3.05	17.20 to 29.20	20.73 ± 2.31	17.00 to 26.40	19.38 ± 2.48	16.40 to 24.50	18.20 ± 1.82	15.30 to 22.20	34.316	< 0.001^b
Central layer	15.91 ± 2.34	12.00 to 23.00	15.37 ± 2.99	11.00 to 27.40	14.84 ± 3.46	10.80 to 28.30	13.49 ± 2.68	10.70 to 23.50	22.204	< 0.001^b
(Φ 0–2 mm)	15.91 ± 2.34	12.00 to 23.00	15.37 ± 2.99	11.00 to 27.40	14.84 ± 3.46	10.80 to 28.30	13.49 ± 2.68	10.70 to 23.50	22.204	< 0.001^b
Central layer	13.80 ± 1.80	10.50 to 18.30	13.13 ± 1.45	10.10 to 16.50	12.60 ± 1.64	9.60 to 15.60	11.51 ± 1.46	9.70 to 15.20	20.295	< 0.001^b
(Φ 2–6 mm)	13.80 ± 1.80	10.50 to 18.30	13.13 ± 1.45	10.10 to 16.50	12.60 ± 1.64	9.60 to 15.60	11.51 ± 1.46	9.70 to 15.20	20.295	< 0.001^b
Posterior layer	11.94 ± 2.49	6.00 to 16.20	11.48 ± 3.41	5.80 to 24.40	11.44 ± 3.11	6.60 to 21.40	9.95 ± 2.26	6.50 to 15.50	10.309	< 0.001^b
(Φ 0–2 mm)	11.94 ± 2.49	6.00 to 16.20	11.48 ± 3.41	5.80 to 24.40	11.44 ± 3.11	6.60 to 21.40	9.95 ± 2.26	6.50 to 15.50	10.309	< 0.001^b
Posterior layer	12.51 ± 1.74	9.70 to 16.90	11.73 ± 1.21	8.80 to 14.70	11.49 ± 1.36	8.80 to 14.80	10.44 ± 1.29	8.30 to 12.70	15.864	< 0.001^b
(Φ 2–6 mm)	12.51 ± 1.74	9.70 to 16.90	11.73 ± 1.21	8.80 to 14.70	11.49 ± 1.36	8.80 to 14.80	10.44 ± 1.29	8.30 to 12.70	15.864	< 0.001^b
Total layer	17.72 ± 2.74	13.30 to 25.10	16.85 ± 3.36	11.80 to 30.00	16.39 ± 3.81	11.30 to 30.80	14.94 ± 2.74	11.70 to 25.10	16.972	< 0.001^b
(Φ 0–2 mm)	17.72 ± 2.74	13.30 to 25.10	16.85 ± 3.36	11.80 to 30.00	16.39 ± 3.81	11.30 to 30.80	14.94 ± 2.74	11.70 to 25.10	16.972	< 0.001^b
Total layer	15.99 ± 2.08	12.70 to 21.30	15.20 ± 1.48	12.90 to 19.20	14.49 ± 1.75	11.70 to 18.30	13.40 ± 1.37	11.50 to 16.50	26.231	< 0.001^b
(Φ 2–6 mm)	15.99 ± 2.08	12.70 to 21.30	15.20 ± 1.48	12.90 to 19.20	14.49 ± 1.75	11.70 to 18.30	13.40 ± 1.37	11.50 to 16.50	26.231	< 0.001^b

Φ Annular diameters, ^a Mixed linear model analysis, ^bA significant difference was detected

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