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Table 1 Treatment characteristics between groups

From: Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients

  Clinical grading of retinal toxicity ALL eyes P value
None grade 1 grade 2 grade 3 grade 4 grade 5
Number of eyes 11 4 3 3 3 6 30  
Mean number of IVC rounds(n = 20) 5.8 6.0 6.0 6.5 7.0 7.3 6.3 0.3013
Mean number of IAC rounds(n = 13) 3.3 3.5 3.0 3.5 4.0 3.0 3.4 0.9937
Mean number of IVM injections 2.7 3.0 2.3 3.0 2.3 2.8 2.7 0.8613
Mean dosage given (μg) 22.2 25.5 23.7 25.0 29.3 27.8 24.9 0.0045
Mean cumulative total dose(μg) 62.2 77.0 55.3 71.7 69.3 78.7 68.4 0.5306
Abnormal hyaloidal interface 1/11 0/4 1/3 1/3 1/3 1/6 5/30 0.3672
  1. *IVC was conducted in 17 patients, while IAC was conducted in 10 patients. 3 patients recieved both IVC and IAC. The mean number was calculated in those patients who received the therapies. IVC intravenous chemotherapy, IAC intra-arterial chemotherapy, IVM intravitreal melphalan