Table 1 Treatment characteristics between groups
From: Ocular toxicity of intravitreal melphalan for retinoblastoma in Chinese patients
Clinical grading of retinal toxicity | ALL eyes | P value | ||||||
|---|---|---|---|---|---|---|---|---|
None | grade 1 | grade 2 | grade 3 | grade 4 | grade 5 | |||
Number of eyes | 11 | 4 | 3 | 3 | 3 | 6 | 30 | |
Mean number of IVC rounds(n = 20) | 5.8 | 6.0 | 6.0 | 6.5 | 7.0 | 7.3 | 6.3 | 0.3013 |
Mean number of IAC rounds(n = 13) | 3.3 | 3.5 | 3.0 | 3.5 | 4.0 | 3.0 | 3.4 | 0.9937 |
Mean number of IVM injections | 2.7 | 3.0 | 2.3 | 3.0 | 2.3 | 2.8 | 2.7 | 0.8613 |
Mean dosage given (μg) | 22.2 | 25.5 | 23.7 | 25.0 | 29.3 | 27.8 | 24.9 | 0.0045 |
Mean cumulative total dose(μg) | 62.2 | 77.0 | 55.3 | 71.7 | 69.3 | 78.7 | 68.4 | 0.5306 |
Abnormal hyaloidal interface | 1/11 | 0/4 | 1/3 | 1/3 | 1/3 | 1/6 | 5/30 | 0.3672 |