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Table 3 Univariate and multivariate Cox regression analyses of glaucoma risk factors in migraine patients

From: Migraine and increased risk of developing open angle glaucoma: a population-based cohort study

 

Univariate

Multivariate

HR (95% CI)

p value

HR (95% CI)

p value

Age

1.04 (1.03, 1.04)

<  0.0001

1.03 (1.03, 1.04)

<  0.0001

Women

0.84 (0.70, 1.02)

0.0721

  

Charlson’s score

 Hyperlipidemia

2.94 (2.26, 3.81)

<  0.0001

1.54 (1.16, 2.05)

0.003

 Ischemic heart disease

2.60 (1.92, 3.52)

<  0.0001

1.15 (0.83, 1.59)

0.4098

 Hypertension

2.63 (2.17, 3.18)

<  0.0001

1.23 (0.98, 1.56)

0.0765

 Myocardial Infarction

2.59 (0.65, 10.38)

0.1793

  

 Congestive Heart Failure

1.46 (0.65, 3.26)

0.3576

  

 Peripheral Vascular Disease

3.82 (1.98, 7.38)

0.0001

1.87 (0.96, 3.65)

0.0658

 Cerebrovascular Disease

2.19 (1.47, 3.28)

0.0001

0.93 (0.61, 1.41)

0.735

 Dementia

0.90 (0.13, 6.38)

0.9178

  

 COPD

1.66 (1.21, 2.27)

0.0017

1.02 (0.74, 1.41)

0.8841

 Connective Tissue Disease

2.17 (1.19, 3.93)

0.0111

1.56 (0.86, 2.84)

0.1451

 Peptic Ulcer Disease

1.57 (1.19, 2.09)

0.0015

1.05 (0.79, 1.40)

0.7382

 Mild liver Disease

1.69 (1.17, 2.44)

0.0052

1.20 (0.83, 1.74)

0.3347

 DM

3.19 (2.50, 4.07)

<  0.0001

1.61 (1.25, 2.24)

0.0006

 Hemiplegia

1.23 (0.31, 4.92)

0.7726

  

 Moderate to severe Kidney Disease

3.00 (0.75, 12.01)

0.1214

  

 Solid Tumor

1.93 (1.14, 3.28)

0.0152

1.24 (0.73, 2.12)

0.4295

  1. COPD chronic obstructive pulmonary disease, DM diabetes mellitus