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Table 3 Univariate and multivariate Cox regression analyses of glaucoma risk factors in migraine patients

From: Migraine and increased risk of developing open angle glaucoma: a population-based cohort study

  Univariate Multivariate
HR (95% CI) p value HR (95% CI) p value
Age 1.04 (1.03, 1.04) <  0.0001 1.03 (1.03, 1.04) <  0.0001
Women 0.84 (0.70, 1.02) 0.0721   
Charlson’s score
 Hyperlipidemia 2.94 (2.26, 3.81) <  0.0001 1.54 (1.16, 2.05) 0.003
 Ischemic heart disease 2.60 (1.92, 3.52) <  0.0001 1.15 (0.83, 1.59) 0.4098
 Hypertension 2.63 (2.17, 3.18) <  0.0001 1.23 (0.98, 1.56) 0.0765
 Myocardial Infarction 2.59 (0.65, 10.38) 0.1793   
 Congestive Heart Failure 1.46 (0.65, 3.26) 0.3576   
 Peripheral Vascular Disease 3.82 (1.98, 7.38) 0.0001 1.87 (0.96, 3.65) 0.0658
 Cerebrovascular Disease 2.19 (1.47, 3.28) 0.0001 0.93 (0.61, 1.41) 0.735
 Dementia 0.90 (0.13, 6.38) 0.9178   
 COPD 1.66 (1.21, 2.27) 0.0017 1.02 (0.74, 1.41) 0.8841
 Connective Tissue Disease 2.17 (1.19, 3.93) 0.0111 1.56 (0.86, 2.84) 0.1451
 Peptic Ulcer Disease 1.57 (1.19, 2.09) 0.0015 1.05 (0.79, 1.40) 0.7382
 Mild liver Disease 1.69 (1.17, 2.44) 0.0052 1.20 (0.83, 1.74) 0.3347
 DM 3.19 (2.50, 4.07) <  0.0001 1.61 (1.25, 2.24) 0.0006
 Hemiplegia 1.23 (0.31, 4.92) 0.7726   
 Moderate to severe Kidney Disease 3.00 (0.75, 12.01) 0.1214   
 Solid Tumor 1.93 (1.14, 3.28) 0.0152 1.24 (0.73, 2.12) 0.4295
  1. COPD chronic obstructive pulmonary disease, DM diabetes mellitus