Table 2 Comparison of ocular surface characteristics between the paediatric and adult blepharokeratoconjunctivitis groups
BKC | Control | P-value | ||||||
|---|---|---|---|---|---|---|---|---|
Paediatric | Adult | Paediatric | Adult | (a)vs(c) | (b)vs(d) | (a)vs(b) | (c)vs(d) | |
(a) | (b) | (c) | (d) | |||||
TBUT (seconds) | 3.7 ± 1.3 | 3.1 ± 0.9 | 8.2 ± 1.8 | 7.0 ± 2.3 | < 0.001a | < 0.001a | 0.097 | 0.310 |
ST (mm/5 min) | 15.1 ± 8.8 | 11.0 ± 8.8 | 18.4 ± 8.8 | 13.2 ± 7.6 | 0.278 | 0.092 | 0.029a | 0.037a |
Corneal disorder | ||||||||
Corneal staining | 3.6 ± 1.8 | 2.8 ± 1.6 | 0.1 ± 0.2 | 0.1 ± 0.2 | < 0.001a | < 0.001a | 0.169 | 0.980 |
neovascularization | 11.8 ± 4.3 | 4.3 ± 5.3 | – | – | – | – | 0.001a | – |
infiltration | 44%(8/18) | 31%(10/32) | – | – | – | – | 0.351 | – |
ulceration | 6%(1/18) | 13%(4/32) | – | – | – | – | 0.642 | – |
scarring | 61%(11/18) | 31%(10/32) | – | – | – | – | 0.040a | – |
Lid margin | ||||||||
hyperemia | 50%(9/18) | 69%(22/32) | – | – | – | – | 0.190 | – |
telangiectasia | 56%(10/18) | 75%(24/32) | – | – | – | – | 0.157 | – |
secretion | 50%(9/18) | 59%(19/32) | – | – | – | – | 0.522 | – |
Meibum quality | 4.1 ± 3.6 | 7.0 ± 3.0 | 0.3 ± 1.0 | 1.0 ± 1.6 | < 0.001a | < 0.001a | 0.008a | 0.066 |
Meibum expressibility | 1.3 ± 1.2 | 1.8 ± 1.2 | 0.0 ± 0.0 | 0.4 ± 0.7 | < 0.001a | < 0.001a | 0.175 | 0.019a |