Table 4 Multivariable analysis of vision improvement for the PRN pattern and three-injections pattern

 >60 years

1.0 (reference)

1.0 (reference)

1.0 (reference)

1.0 (reference)

 50 to 60 years

1.18 (0.92-1.50)

0.189

3.25 (1.86-5.67)

0.000*

1.87 (1.00-3.51)

0.051

3.99 (1.48-10.76)

0.006*

 <50 years

1.23 (0.95-1.58)

0.113

2.92 (1.4-6.07)

0.004*

2.24 (1.10-4.56)

0.027*

18.38 (4.61-73.36)

0.000*

 Male

1.0 (reference)

1.0 (reference)

1.0 (reference)

1.0 (reference)

 Female

1.03 (0.84-1.26)

0.788

0.8 (0.47-1.39)

0.434

1.34 (0.80-2.27)

0.271

1.20 (0.53-2.73)

0.668

 IVB

1.0 (reference)

1.0 (reference)

1.0 (reference)

1.0 (reference)

 IVR

1.20 (0.68-2.12)

0.691

1.18 (0.68-2.05)

0.561

0.48 (0.20-1.17)

0.109

0.86 (0.35-2.14)

0.753

 DM with other comorbidities

1.0 (reference)

1.0 (reference)

1.0 (reference)

1.0 (reference)

 DM without other comorbidities

1.27 (0.90-1.80)

0.179

1.02 (0.42-2.51)

0.961

0.41 (0.11-1.61)

0.202

0.16 (0.03-0.76)

0.021*

 non-DM with other comorbidities

1.52 (1.15-2.01)

0.003*

0.91 (0.39-2.12)

0.819

1.31 (0.70-2.43)

0.400

0.83 (0.17-4.11)

0.817

 non-DM without other comorbidities

1.55 (1.16-20.7)

0.003*

1.52 (0.63-3.65)

0.349

2.14 (1.06-4.32)

0.034*

0.70 (0.15-3.24)

0.645

 Other diseases

1.0 (reference)

1.0 (reference)

1.0 (reference)

1.0 (reference)

 nAMD and PCV

1.57 (1.06-2.32)

0.023*

1.66 (0.73-3.78)

0.226

1.12 (0.48-2.63)

0.787

2.36 (0.52-10.7)

0.266

 DME

1.32 (0.93-1.87)

0.126

1.39 (0.49-3.97)

0.535

1.21 (0.50-2.94)

0.675

0.88 (0.15-5.13)

0.883

 RVO

3.66 (2.50-5.36)

0.000*

2.76 (1.20-6.34)

0.017*

2.26 (0.93-5.48)

0.072

2.39 (0.66-8.62)

0.182

 PDR

1.25 (0.87-1.80)

0.223

0.85 (0.30-2.41)

0.756

0.88 (0.26-3.01)

0.835

0.42 (0.04-4.09)

0.454

 Baseline VA^a

1.05 (1.04-1.07)

0.000*

1.08 (1.04-1.13)

0.000*

1.08 (1.04-1.13)

0.001*

1.10 (1.02-1.18)

0.009*

 Number of drug injections^a

1.27 (1.06-1.54)

0.012*

1.43 (1.14-1.78)

0.002*

-

-

-

-