Fig. 2

NOX2 and NOX4 expression under cyclic stretch in ARPE-19 cells based on Western blotting. The NOX2 expression was significantly increased at 24 h by cyclic stretch (p = 0.020). There was no significant difference between the control, 15 min, 2 h, 6 h, 12 h group(p = 0.851, 0.586, 0.811, 0.453). The NOX4 expression was significantly increased at 2 h, 6 h, 12 h and 24 h by cyclic stretch (p < 0.01,< 0.01,< 0.01,< 0.01). There was no significant difference between the control and the 15 min group(p = 0.316)