| 0 | 4 weeks | 12 weeks | Difference (0–4 weeks) a | Difference (0–12 weeks)a | P value (0–12 weeks)b |
---|---|---|---|---|---|---|
CN | 10.78 ± 5.02 (4.00~27.00) | 6.03 ± 3.67 (1.00~17.00) | 4.17 ± 3.57 (0.00~16.00) | −4.74 ± 4.63 (−26.00~3.00) | −6.60 ± 4.47 (− 22.00~3.00) | < 0.0001 |
DQ | 10.25 ± 4.89 (4.00~23.00) | 6.21 ± 4.36 (1.00~24.00) | 3.61 ± 3.45 (0.00~16.00) | −4.04 ± 4.12 (−17.00~3.00) | −6.63 ± 4.72 (− 18.00~7.00) | < 0.0001 |
P value | 0.5220 | 0.9708 | 0.3214 | 0.4860 | 0.9739 | Â |