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Table 2 Changes of Corneaconjunctival Staining Score (NEI score) between CN and DQ group

From: RETRACTED ARTICLE: Comparison of 0.05% cyclosporine and 3% diquafosol solution for dry eye patients: a randomized, blinded, multicenter clinical trial

 

0

4 weeks

12 weeks

Difference (0–4 weeks) a

Difference (0–12 weeks)a

P value (0–12 weeks)b

CN

10.78 ± 5.02 (4.00~27.00)

6.03 ± 3.67 (1.00~17.00)

4.17 ± 3.57 (0.00~16.00)

−4.74 ± 4.63 (−26.00~3.00)

−6.60 ± 4.47 (− 22.00~3.00)

< 0.0001

DQ

10.25 ± 4.89 (4.00~23.00)

6.21 ± 4.36 (1.00~24.00)

3.61 ± 3.45 (0.00~16.00)

−4.04 ± 4.12 (−17.00~3.00)

−6.63 ± 4.72 (− 18.00~7.00)

< 0.0001

P value

0.5220

0.9708

0.3214

0.4860

0.9739

 
  1. CN 0.05% cyclosporin nanoemusion (0.5 mg/mL), DQ 3% diquafosol sodium (30 mg/mL)
  2. aComparison between CN and DQ groups by Wilcoxon rank sum test
  3. bComparison among three groups by Kruskal-Wallis test