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Fig. 1 | BMC Ophthalmology

Fig. 1

From: Nerve growth factor promotes the proliferation of Müller cells co-cultured with internal limiting membrane by regulating cell cycle via Trk-A/PI3K/Akt pathway

Fig. 1

Effects of NGF, ILM and NGF + ILM on the proliferation of Müller cells. a CCK8 assay results of cell growth in different groups (Control, NGF, ILM, NGF + ILM). **P < 0.01, NGF/ILM/NGF + ILM vs Control at each time point; #P < 0.05, ##P < 0.01, ILM + NGF vs NGF at each time point; ^^P < 0.01 ILM + NGF vs ILM at each time point. b The expression of p-Trk-A, Trk-A, p-Akt and Akt were evaluated by Western blot using specific primary antibodies in four different groups of Müller cells. c Quantitative analysis of protein levels of p-Trk-A, Trk-A p-Trk-A/rk-A and p-Akt/Akt in panel b. * indicates NGF/ILM/NGF+ILM vs Control; # indicates ILM+NGF vs NGF; ^^ indicates ILM+NGF vs ILM at each time point. *, ^, #, P < 0.05; **, ^^, ##, P < 0.01

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BMC Ophthalmology

ISSN: 1471-2415

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