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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Nerve growth factor promotes the proliferation of Müller cells co-cultured with internal limiting membrane by regulating cell cycle via Trk-A/PI3K/Akt pathway

Fig. 2

Effects of NGF, ILM and NGF + ILM on cell cycle progression of Müller cells. a The images of cell cycle analyses result in four different groups of Müller cells (upper panel), and the percentage of each phase (G1-M) is indicated (lower panel). Light blue indicates cell debris; light green indicates cell aggregates; red indicates G1-phase (left) and G2-phase (right) cells; and the oblique line indicates S-phase cells. Relative mRNA levels (b) and protein levels (c) of CyclinD1, CyclinE, CDK2, CDK4, and p21 in four different groups of Müller cells. *P < 0.05, **P < 0.01 NGF/ILM/NGF + ILM vs Control; #P < 0.05, ## P < 0.01, ILM + NGF vs NGF; ^P < 0.05, ^^P < 0.01 ILM + NGF vs ILM

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BMC Ophthalmology

ISSN: 1471-2415

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