Fig. 4
From: Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation
UVA-irradiation led to loss of mitochondrial membrane potential and induced mitochondria-related apoptotic pathways in the AREP-19 cells. a Cells were exposed to UVA (0, 5 and 10 J/cm2), stained with JC-1 dye, and imaged under fluorescent microscopy. b Western blotting data showed changes in pro-caspase-3, cleaved-caspase-3, pro-caspase-9, cleaved-caspase-9, Mcl-1, Bcl-xl, Bcl-2, Bax, Bad, p-Bad, AIF, and cytosolic cytochrome C expression in AREP-19 cells exposed to UVA. β-actin was used as an internal control