Table 3 Diagnostic Criteria of Fraser Syndrome2
From: Reconstruction strategy in isolated complete Cryptophthalmos: a case series
Criterion | Characteristics |
|---|---|
Major | Cryptophthalmos (complete, incomplete, or abortive form) |
Syndactyly | |
Genital abnormalities (male patients: cryptorchidism, hypospadias) (female patients: uterine abnormalities, malformed fallopian tubes, clitoromegaly) | |
Affected sibling | |
Minor | Nasal malformations |
Ear malformations | |
Laryngeal malformations | |
Umbilical hernia | |
Renal abnormalities (dysplasia, hypoplasia, or agenesis) | |
Bony abnormalities (other than syndactyly) | |
Cleavage of tongue or other oral clefts | |
Mental retardation |