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Table 3 Previous studies on optical coherence tomography angiography in amblyopia

From: Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography

      

FAZ area

VD (3 × 3 mm scan)

 

Study

OCTA (algorithm)

Patients with amblyopia

Age (years)

LogMAR of AE

Type of amblyopia

SCP

DCP

SCP

DCP

FMT

Lonngi M, 2017 [15]

RTVue XR Avanti (SSADA)

13

8.0 ± 4.0

0.51 ± 0.17

Anisometropia, strabismus

No difference

No difference

No difference

No difference

No difference

Yilmaz I, 2017 [16]

RTVue XR Avanti (SSADA)

15

8.2 ± 2.3

0.25 ± 0.06

Strabismus

No difference

No difference

Decreased in AE

Decreased in AE

Sobral I, 2018 [17]

RTVue XR Avanti (SSADA)

26

9.2 ± 2.8

0.18 ± 0.21

Anisometropia, strabismus

No difference

Increased in AE

Decreased in AE

No difference

No difference

Demirayak B, 2019 [18]

RTVue XR Avanti (SSADA)

17

8.6 ± 2.5

0.32 ± 0.06

Anisometropia, strabismus

No difference

No difference

No difference

No difference

Our study

NIDEK RS-3000 Advance (CODAA)

15

9.8 ± 3.4

0.21 ± 0.24

Anisometropia, mixed

Decreased in AE

No difference

No difference§

No difference§

No difference

  1. AE: amblyopic eyes, CODAA: complex OCT-signal difference analysis angiography, DCP: deep capillary plexus, FAZ: foveal avascular zone, FMT: foveal minimum thickness, LogMAR: logarithm of the minimum angle of resolution, OCTA: optical coherence tomography angiography, SCP: superficial capillary plexus, SSADA: split-spectrum amplitude-decorrelation algorithm, VD: vessel density
  2. VD in a 6 × 6-mm area is decreased in amblyopic eyes. No significant difference is evident between amblyopic and fellow eyes, but a significant difference is present between amblyopic and normal control eyes. § The analysis region of the OCTA image was 2.3 × 2.3-mm after magnification correction. Values are shown as mean ± standard deviation