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Table 3 Previous studies on optical coherence tomography angiography in amblyopia

From: Foveal avascular zone and macular vessel density after correction for magnification error in unilateral amblyopia using optical coherence tomography angiography

       FAZ area VD (3 × 3 mm scan)  
Study OCTA (algorithm) Patients with amblyopia Age (years) LogMAR of AE Type of amblyopia SCP DCP SCP DCP FMT
Lonngi M, 2017 [15] RTVue XR Avanti (SSADA) 13 8.0 ± 4.0 0.51 ± 0.17 Anisometropia, strabismus No difference No difference No difference No difference No difference
Yilmaz I, 2017 [16] RTVue XR Avanti (SSADA) 15 8.2 ± 2.3 0.25 ± 0.06 Strabismus No difference No difference Decreased in AE Decreased in AE
Sobral I, 2018 [17] RTVue XR Avanti (SSADA) 26 9.2 ± 2.8 0.18 ± 0.21 Anisometropia, strabismus No difference Increased in AE Decreased in AE No difference No difference
Demirayak B, 2019 [18] RTVue XR Avanti (SSADA) 17 8.6 ± 2.5 0.32 ± 0.06 Anisometropia, strabismus No difference No difference No difference No difference
Our study NIDEK RS-3000 Advance (CODAA) 15 9.8 ± 3.4 0.21 ± 0.24 Anisometropia, mixed Decreased in AE No difference No difference§ No difference§ No difference
  1. AE: amblyopic eyes, CODAA: complex OCT-signal difference analysis angiography, DCP: deep capillary plexus, FAZ: foveal avascular zone, FMT: foveal minimum thickness, LogMAR: logarithm of the minimum angle of resolution, OCTA: optical coherence tomography angiography, SCP: superficial capillary plexus, SSADA: split-spectrum amplitude-decorrelation algorithm, VD: vessel density
  2. VD in a 6 × 6-mm area is decreased in amblyopic eyes. No significant difference is evident between amblyopic and fellow eyes, but a significant difference is present between amblyopic and normal control eyes. § The analysis region of the OCTA image was 2.3 × 2.3-mm after magnification correction. Values are shown as mean ± standard deviation