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Table 1 Epidemiologic Characteristics and Ophthalmologic Clinical Presentation of Patients

From: Choroidal structural changes correlate with severity of diabetic retinopathy in diabetes mellitus

 

Control

DM with no DR

PRP-untreated NPDR

PRP-untreated PDR

P value

Number of eyes (n)

38

22

24

20

 

Age (year), mean ± SD

63.42 ± 7.24

61.77 ± 7.63

61.83 ± 8.62

63.55 ± 6.39

P = 0.739*

Gender (male/female)

21/17

12/10

12/12

9/11

P = 0.457#

Years with diabetes (year), mean ± SD

5.23 ± 1.31

9.85 ± 2.32

11.68 ± 2.63

P < 0.001*,†

BMI (kg/m2), mean ± SD

24.38 ± 2.53

26.06 ± 2.53

24.64 ± 3.94

23.77 ± 3.22

P = 0.090*

HbA1c (%), mean ± SD

7.54 ± 0.76

7.96 ± 0.84

8.51 ± 0.96

P = 0.002*

Fasting blood glucose (mmol/L), mean ± SD

7.37 ± 0.73

7.53 ± 0.91

7.85 ± 1.01

P = 0.218*

Systolic BP (mmHg), mean ± SD

124.76 ± 3.78

122.36 ± 5.49

123.54 ± 4.36

124.75 ± 4.96

P = 0.202*

Diastolic BP (mmHg), mean ± SD

80.16 ± 5.81

79.64 ± 5.21

78.96 ± 5.38

79.55 ± 4.83

P = 0.865*

Diabetic nephropathy (n)

0

0

3

5

IOP (mmHg), mean ± SD

15.12 ± 1.48

15.14 ± 2.71

15.05 ± 3.23

13.95 ± 4.02

P = 0.434*

Axial length (mm), mean ± SD

24.10 ± 0.64

23.86 ± 0.67

24.27 ± 0.55

24.01 ± 0.59

P = 0.149*

Treatment with insulin, n (%)

0

19 (86.3)

23 (95.8)

20 (100)

  1. SD, standard deviation; BMI, body mass index; BP, blood pressure; DM, diabetes mellitus; DR, diabetic retinopathy; PDR, proliferative diabetic retinopathy; NPDR, non-proliferative diabetic retinopathy; IOP, intraocular pressure
  2. *: Statistical significance tested by ANOVA for normal distributions and Kruskal–Wallis tests for nonnormal distributions; all comparisons were corrected with the post hoc test
  3. #: P values were calculated using the Fisher’s exact test
  4. †: Significant difference between mean values of DM with no DR, PRP-untreated NPDR, PRP-untreated PDR eyes